no evidence of human herpesvirus 8 among iranian patients infected with hiv

نویسندگان

amitis ramezani

elham saboori

kayhan azadmanesh

minoo mohraz

چکیده

background: kaposi’s sarcoma is a vascular malignancy, which frequently occurs among immunocompromised individuals such as transplant recipients and patients with acquired immunodeficiency syndrome. human herpesvirus 8 (hhv-8) is considered the etiological agent of all forms of kaposi’s sarcoma. though some seroepidemiological studies conducted on the prevalence of hhv-8 in iran, there are insufficient data on the prevalence of hhv-8 viremia in hiv infected patients. we therefore, aimed to determine the prevalence of hhv-8 viremia in general population and hiv infected patients without kaposi’s sarcoma in tehran, iran. methods: we conducted a cross sectional survey on 99 patients with hiv infection referred to iranian research center for hiv/aids and 40 healthy controls in tehran, iran from january to april 2014. the presence of hhv-8 dna was detected in buffy coat samples of enrolled subjects using nested pcr assay. results: a total of 99 hiv infected patients with mean age of 37.9±10 yr and 40 healthy controls with mean age of 39±11.5 yr were enrolled in the study. the mean cd4 count was 410.3± 211.4 cells/mm 3 . hhv-8 dna was not detected in both healthy control and hiv patient groups. conclusion: this survey showed low rate of hhv-8 dna in healthy controls and hiv patients. considering our findings hhv-8 infection does not seem to be widespread in our population. further studies focusing on different regions of iran appear to be required to have a more accurate estimation.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

No Evidence of Human Herpesvirus 8 among Iranian Patients Infected with HIV

BACKGROUND Kaposi's sarcoma is a vascular malignancy, which frequently occurs among immunocompromised individuals such as transplant recipients and patients with acquired immunodeficiency syndrome. Human herpesvirus 8 (HHV-8) is considered the etiological agent of all forms of Kaposi's sarcoma. Though some seroepidemiological studies conducted on the prevalence of HHV-8 in Iran, there are insuf...

متن کامل

No Evidence for Human Papillomavirus in Patients with HIV in Iran

Background: Human Papillomaviruses (HPVs) have anestablished role in the development of cervical cancer. However, the presence of underlying conditions such as HIV/AIDS is necessary for this to occur. This studyaimed to evaluate the prevalence of HPV DNA in plasma samples from HIV-positive patients in Tehran, Iran. Methods: Plasma specimens from 95 patients diagnosed with HIV infection from Te...

متن کامل

Distribution of Epstein-Barr Virus and Human Herpesvirus 8 Co-Infections among Human Immunodeficiency Virus -1 Positive Patients

Background and Aims: Among Human Immunodeficiency Virus (HIV)-infected individuals, Epstein-Barr virus (EBV) and Human Herpesvirus (HHV)-8 could cause significant illness as opportunistic infections. The purpose of the present study was to evaluate the prevalence of EBV and HHV-8 in saliva specimens obtained from HIV-1 infected Iranian individuals under the Highly Active Antiviral Therapy (HAAR...

متن کامل

Antibody responses to lytic and latent human herpesvirus 8 antigens among HIV-infected patients in central China.

Human herpesvirus 8 (HHV8) is an important opportunistic infection of HIV/AIDS. However, very little is known about antibody seropositivities to HHV8 lytic and latent antigens among HIV-infected patients in China. Therefore, a cross-sectional study was conducted to explore HHV8 serostatus among 316 HIV-infected patients in a rural area of central China. The antibody seropositivity to HHV8 ORF65...

متن کامل

Coinfection with Human Herpesvirus 8 Is Associated with Persistent Inflammation and Immune Activation in Virologically Suppressed HIV-Infected Patients

OBJECTIVES Infection with co-pathogens is one of the postulated factors contributing to persistent inflammation and non-AIDS events in virologically-suppressed HIV-infected patients. We aimed to investigate the relationship of human herpesvirus-8 (HHV-8), a vasculotropic virus implicated in the pathogenesis of Kaposi's sarcoma, with inflammation and subclinical atherosclerosis in HIV-infected p...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of public health

جلد ۴۵، شماره ۷، صفحات ۹۳۵-۹۴۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023